Neutrophil:Lymphocyte Ratios Have Prognostic Value in Triple-Negative Breast Cancer
نویسندگان
چکیده
منابع مشابه
Prognostic markers in triple-negative breast cancer.
BACKGROUND Triple-negative breast cancer (estrogen receptor-negative, progesterone receptor-negative, and HER2-negative) is a high risk breast cancer that lacks the benefit of specific therapy that targets these proteins. METHODS In this study, the authors examined a large and well characterized series of invasive breast carcinoma (n = 1944) with a long-term clinical follow-up (median, 56 mon...
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Triple-negative breast cancer (TNBC) has a significant clinical relevance of being associated with a shorter median time to relapse and death and does not respond to endocrine therapy or other available targeted agents. Increased aggressiveness of this tumor, as well as resistance to standard drug therapies, may be associated with the presence of stem cell populations within the tumor. Several ...
متن کاملThe significant prognostic value of circulating tumor cells in triple-negative breast cancer: a meta-analysis
BACKGROUND The clinical validity of circulating tumor cells (CTCs) is still controversial in patients with triple-negative breast cancer (TNBC). METHODS A comprehensive literature search was performed to identify relevant articles in the PubMed, Web of Science, MEDLINE, and Embase databases through September 2015. The outcomes of interest were disease progression and overall survival. The haz...
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BACKGROUND Androgen receptor (AR) is a promising therapeutic target for breast cancer. However, its prognostic value remains controversial in triple negative breast cancer (TNBC). Here we present a meta-analysis to investigate the correlation between AR expression and TNBC prognosis. RESULTS Thirteen relevant studies with 2826 TNBC patients were included. AR positive rate was 24.4%. AR+ patie...
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This study was to investigate the prognostic role of Ki-67 in further classification of triple negative breast cancer (TNBC), and to test whether high expression level of Ki67 can predict benefit from carboplatin. From January 2004 to December 2012, 363 patients operated for TNBC were identified through the institutional clinical database. After a median follow-up time of 34 months (5.2-120.0 m...
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ژورنال
عنوان ژورنال: Journal of Nihon University Medical Association
سال: 2017
ISSN: 0029-0424,1884-0779
DOI: 10.4264/numa.76.5_195